Msx1^tm1Rilm
Targeted Allele Detail

Summary

• Symbol: Msx1^tm1Rilm
• Name: msh homeobox 1; targeted mutation 1, Richard Maas
• MGI ID: MGI:1926386
• Synonyms: Msx1-
• Gene: Msx1 Location: Chr5:37977835-37981929 bp, - strand Genetic Position: Chr5, 20.21 cM
• Alliance: Msx1^tm1Rilm page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:17489
• Parent Cell Line: J1 (ES Cell)
• Strain of Origin: 129S4/SvJae

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• Mutation details: Gene disruption caused by insertion of a pMC1-neo cassette into coding sequences located in the homeobox domain. (J:17489)

Disease models

Expression

In Mice Carrying this Mutation:	330 assay results 2 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	17 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Msx1 Mutation: 18 strains or lines available

References

• Original: J:17489 Satokata I, et al., Msx1 deficient mice exhibit cleft palate and abnormalities of craniofacial and tooth development [see comments]. Nat Genet. 1994 Apr;6(4):348-56
• All: 42 reference(s)