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Hoxc13tm2Mrc
Targeted Allele Detail
Summary
Symbol: Hoxc13tm2Mrc
Name: homeobox C13; targeted mutation 2, Mario R Capecchi
MGI ID: MGI:1926425
Synonyms: Hoxc13lacZ
Gene: Hoxc13  Location: Chr15:102829566-102837249 bp, + strand  Genetic Position: Chr15, Syntenic
Alliance: Hoxc13tm2Mrc page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:45400
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion
    In-frame insertion of the LacZ gene into DNA sequences encoding the homeodomain. (J:45400)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 8 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hoxc13 Mutation:  15 strains or lines available
References
Original:  J:45400 Godwin AR, et al., Hoxc13 mutant mice lack external hair. Genes Dev. 1998 Jan 1;12(1):11-20
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory