Tg(Foxn1)6Jlb
Transgene Detail

Summary

• Symbol: Tg(Foxn1)6Jlb
• Name: transgene insertion 6, Janice L Brissette
• MGI ID: MGI:1926457
• Synonyms: inv-whn, T6
• Transgene: Tg(Foxn1)6Jlb Location: unknown
• Alliance: Tg(Foxn1)6Jlb page

Transgene origin

• Strain of Origin: DBA x C57BL/6

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Foxn1)6Jlb expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Foxn1 (MGI:102949)

• Mutation details: Overexpression of the mouse Foxn1 gene in the epidermis, hair follicles, urothelium and stratified epithelia, driven by the human involucrin (INV) promoter. (J:56641)
• Inheritance: Not Specified

Expression

In Structures Affected by this Mutation:

7 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

Notes

Founder number 6 is representative of a number of founders that are runted at birth and never reach similar size to non-transgenic littermates. These founder numbers were designated as 6, 9 and 11.

See Tg(Foxn1)1Jlb for variability in phenotypes using this construct.

References

• Original: J:56641 Prowse DM, et al., Ectopic expression of the nude gene induces hyperproliferation and defects in differentiation: implications for the self-renewal of cutaneous epithelia. Dev Biol. 1999 Aug 1;212(1):54-67
• All: 1 reference(s)