Tg(Il6)1Efu
Transgene Detail

Summary

• Symbol: Tg(Il6)1Efu
• Name: transgene insertion 1, Elaine Fuchs
• MGI ID: MGI:1926480
• Synonyms: K14-Il-6
• Transgene: Tg(Il6)1Efu Location: unknown
• Alliance: Tg(Il6)1Efu page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Il6)1Efu expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Il6 (MGI:96559)

• Tg(Il6)1Efu expression driven by 1 gene
  Transgene expression driven by:
  

  Organism

  Driver Gene

  Homolog in Mouse

  Note

  human

  KRT15 (3866)

  Krt15

  (MGI:96689)

• Mutation details: Overexpression of mouse interleukin 6 (Il6) in stratified squamous epithelia driven by the human keratin 14 (KRT14) promoter. (J:1133)
• Inheritance: Not Specified

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:1133 Turksen K, et al., Interleukin 6: insights to its function in skin by overexpression in transgenic mice. Proc Natl Acad Sci U S A. 1992 Jun 1;89(11):5068-72
• All: 2 reference(s)