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Tg(KRT16)10Cou
Transgene Detail
Summary
Symbol: Tg(KRT16)10Cou
Name: transgene insertion 10, Pierre Coulombe
MGI ID: MGI:1926503
Synonyms: K16
Transgene: Tg(KRT16)10Cou  Location: unknown  
Alliance: Tg(KRT16)10Cou page
Transgene
origin
Strain of Origin:  (C57BL/6 x C3H)F2
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(KRT16)10Cou expresses 1 gene
 
Mutation detailsOverexpression of human keratin 16 (KRT16) in the basal layer of the epidermis, driven by the human keratin 14 (KRT14) promoter. (J:49421)
Inheritance:    Not Specified
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 5 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Notes
Founder number 10 is representative of a number of founders that were examined. The other founder numbers were designated 6 and 21 and were not phenotypically distinguished.

See Tg(KRT16)13Cou for variability in phenotypes using this construct.

References
Original:  J:49421 Paladini RD, et al., Directed expression of keratin 16 to the progenitor basal cells of transgenic mouse skin delays skin maturation. J Cell Biol. 1998 Aug 24;142(4):1035-51
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory