Fign^tm1Frk
Targeted Allele Detail

Summary

• Symbol: Fign^tm1Frk
• Name: fidgetin; targeted mutation 1, Wayne N Frankel
• MGI ID: MGI:1926595
• Gene: Fign Location: Chr2:63801852-63928382 bp, - strand Genetic Position: Chr2, 37.19 cM
• Alliance: Fign^tm1Frk page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:64964
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: A lacZ gene was fused in-frame into exon 4. A neomycin resistance cassette followed the lacZ gene. A FIGN-beta galactosidase fusion protein is predicted to be expressed from this allele. (J:64964)

Expression

In Mice Carrying this Mutation:	10 assay results
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Fign Mutation: 39 strains or lines available

References

• Original: J:64964 Cox GA, et al., The mouse fidgetin gene defines a new role for AAA family proteins in mammalian development. Nat Genet. 2000 Oct;26(2):198-202
• All: 4 reference(s)