Tg(LEF1)1Efu
Transgene Detail

Summary

• Symbol: Tg(LEF1)1Efu
• Name: transgene insertion 1, Elaine Fuchs
• MGI ID: MGI:1926596
• Synonyms: K14-LEF1
• Transgene: Tg(LEF1)1Efu Location: unknown
• Alliance: Tg(LEF1)1Efu page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(LEF1)1Efu expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  LEF1 (51176)

  Lef1	(MGI:96770)

• Mutation details: Overexpression of human LEF1 gene in basal epidermis and the outer root sheath of hair follicles driven by the human K14 (KRT14) promoter. (J:24350)
• Inheritance: Not Specified

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

Notes

3 founder animals; derived mouse lines not distinguished in paper.

References

• Original: J:24350 Zhou P, et al., Lymphoid enhancer factor 1 directs hair follicle patterning and epithelial cell fate. Genes Dev. 1995 Mar 15;9(6):700-13
• All: 2 reference(s)