Tg(Ngf)47Kma
Transgene Detail

Summary

• Symbol: Tg(Ngf)47Kma
• Name: transgene insertion 47, Kathryn M Albers
• MGI ID: MGI:1926645
• Synonyms: A-47, K14-NGF
• Transgene: Tg(Ngf)47Kma Location: unknown
• Alliance: Tg(Ngf)47Kma page

Transgene origin

• Strain of Origin: (C57BL/6 x C3H)F1

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Ngf)47Kma expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Ngf (MGI:97321)

• Mutation details: Overexpression of mouse NGF in basal keratinocytes of the epidermis and the outer root sheath of hair follicles using a human K14 (KRT14) promoter. This line expresses Ngf at a moderate level (lower than line 56) in stratified epithelium including skin, lining of the oral cavity and forestomach. (J:17131)
• Inheritance: Not Specified

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:17131 Albers KM, et al., Overexpression of nerve growth factor in epidermis of transgenic mice causes hypertrophy of the peripheral nervous system. J Neurosci. 1994 Mar;14(3 Pt 2):1422-32
• All: 4 reference(s)