Tg(Ntf3)1Kma
Transgene Detail

Summary

• Symbol: Tg(Ntf3)1Kma
• Name: transgene insertion 1, Kathryn M Albers
• MGI ID: MGI:1926654
• Synonyms: 696-2, K14-NT-3, NT3+, NT3-OE
• Transgene: Tg(Ntf3)1Kma Location: unknown
• Alliance: Tg(Ntf3)1Kma page

Transgene origin

• Strain of Origin: C3H x C57BL/6

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Ntf3)1Kma expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Ntf3 (MGI:97380)

• Mutation details: Overexpression of mouse Neurotrophin-3 (Ntf3) in basal keratinocytes and outer root sheath of hair follicles driven by the human K14 (KRT14) promoter. (J:34172)
• Inheritance: Not Specified

Expression

In Structures Affected by this Mutation:

7 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

Notes

4 founder mice.

References

• Original: J:34172 Albers KM, et al., Cutaneous overexpression of NT-3 increases sensory and sympathetic neuron number and enhances touch dome and hair follicle innervation. J Cell Biol. 1996 Jul;134(2):487-97
• All: 9 reference(s)