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Tg(rv-CYCLIN)29Dlh
Transgene Detail
Summary
Symbol: Tg(rv-CYCLIN)29Dlh
Name: transgene insertion 29, Donald L Holzschu
MGI ID: MGI:1926798
Synonyms: rv-cyclin
Transgene: Tg(rv-CYCLIN)29Dlh  Location: unknown  
Alliance: Tg(rv-CYCLIN)29Dlh page
Runting and alopecia in Tg(rv-CYCLIN)29Dlh/0 mice

Show the 2 phenotype image(s) involving this allele.

Transgene
origin
Strain of Origin:  (C57BL/6 x SJL)F2
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Mutation detailsOverexpression of walleye epidermal hyperplasia virus type 1 (WDSV1) rv-cyclin in squamous epithelial cells, driven by the bovine keratin-5 (KRT5) promoter. (J:62478)
Inheritance:    Not Specified
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 4 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Notes
Transgenic mouse line number 29 is representative of several other lines with an similar phenotype. These include lines 33, 105, 120, 150 and 180. These lines have some variability in the severity of the phenotypes listed above.
References
Original:  J:62478 Lairmore MD, et al., Squamous epithelial proliferation induced by walleye dermal sarcoma retrovirus cyclin in transgenic mice. Proc Natl Acad Sci U S A. 2000 May 23;97(11):6114-9
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory