Tg(Zfp38)D1Htz
Transgene Detail

Summary

• Symbol: Tg(Zfp38)D1Htz
• Name: transgene insertion D1, Nathaniel Heintz
• MGI ID: MGI:1926806
• Synonyms: BAC169tEGFP, D1
• Transgene: Tg(Zfp38)D1Htz Location: unknown
• Alliance: Tg(Zfp38)D1Htz page

Transgene origin

• Strain of Origin: (C57BL/6 x CBA)F1

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Zfp38)D1Htz expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Zscan21 (MGI:99182)

• Mutation details: Overexpression of Zfp38 by insertion of a transgene consisting of a 131kb BAC construct containing the Zfp38 gene modified with two epitope tags, and appended with an IRES followed by a EGFP marker. Copy number estimated at 6. (J:56546)
• Inheritance: Not Specified

Expression

In Structures Affected by this Mutation:

8 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

Notes

Transgenic mouse line D1 is representative of an additional transgenic mouse line, designated E6, that was described as having an identical phenotype and estimated copy number.

References

• Original: J:56546 Yang XW, et al., BAC-mediated gene-dosage analysis reveals a role for Zipro1 (Ru49/Zfp38) in progenitor cell proliferation in cerebellum and skin [see comments]. Nat Genet. 1999 Aug;22(4):327-35
• All: 1 reference(s)