Tg(Av-E1A)901Gpd
Transgene Detail

Summary

• Symbol: Tg(Av-E1A)901Gpd
• Name: transgene insertion 901, G Paolo Dotto
• MGI ID: MGI:1926807
• Synonyms: 901T, K5T/Ela646
• Transgene: Tg(Av-E1A)901Gpd Location: unknown
• Alliance: Tg(Av-E1A)901Gpd page

Transgene origin

• Strain of Origin: (C57BL/6 x SJL)F1

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: Overexpression of a mutant form of the adenovirus E1A gene lacking the first 29 amino acids of the coding region, driven by the human keratin 5 (KRT5) promoter. (J:65047)
• Inheritance: Not Specified

Expression

In Structures Affected by this Mutation:

5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

Notes

Transgene tightly linked with albino coat color.

References

• Original: J:65047 Missero C, et al., Skin-specific expression of a truncated E1a oncoprotein binding to p105-Rb leads to abnormal hair follicle maturation without increased epidermal proliferation. J Cell Biol. 1993 Jun;121(5):1109-20
• All: 1 reference(s)