Tg(Tgfa)1Efu
Transgene Detail

Summary

• Symbol: Tg(Tgfa)1Efu
• Name: transgene insertion 1, Elaine Fuchs
• MGI ID: MGI:1926812
• Synonyms: K14-TGF-alpha, TGF-alpha-hGH
• Transgene: Tg(Tgfa)1Efu Location: unknown
• Alliance: Tg(Tgfa)1Efu page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Tgfa)1Efu expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  rat

  Tgfa (24827)

  Tgfa	(MGI:98724)

• Mutation details: Overexpression of rat TGFalpha in in basal epithelia and outer root sheath of hair follicles driven by the human K14 (KRT14) promoter. (J:65045)
• Inheritance: Not Specified

Expression

In Structures Affected by this Mutation:

15 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

Notes

Multiple lines established; not distinguished in paper.

References

• Original: J:65045 Vassar R, et al., Transgenic mice provide new insights into the role of TGF-alpha during epidermal development and differentiation. Genes Dev. 1991 May;5(5):714-27
• All: 4 reference(s)