Pax2^tm2(Pax5)Mbu
Targeted Allele Detail

Summary

• Symbol: Pax2^tm2(Pax5)Mbu
• Name: paired box 2; targeted mutation 2, Meinrad Busslinger
• MGI ID: MGI:1926937
• Synonyms: Pax2^5ki
• Gene: Pax2 Location: Chr19:44744484-44826310 bp, + strand Genetic Position: Chr19, 38.09 cM
• Alliance: Pax2^tm2(Pax5)Mbu page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:63683
• Parent Cell Line: E14.1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Conditional ready, Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Pax2^tm2(Pax5)Mbu expresses 1 gene
  Knock-in expresses:
  

  Organism	Expressed Gene	Note
  mouse	Pax5 (MGI:97489)

• Mutation details: Fusion of exon 2 encoding the paired domain to the Pax5 cDNA. The Pax5 cDNA is flanked by loxP sites. This allele contains a LacZ reporter gene 3' to the Pax5 insertion. (J:63683)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pax2 Mutation: 44 strains or lines available

References

• Original: J:63683 Bouchard M, et al., Functional equivalence of the transcription factors pax2 and pax5 in mouse development. Development. 2000 Sep;127(17):3703-13
• All: 2 reference(s)