Fgf6^tm1Thbr
Targeted Allele Detail

Summary

• Symbol: Fgf6^tm1Thbr
• Name: fibroblast growth factor 6; targeted mutation 1, Thomas Braun
• MGI ID: MGI:1927559
• Synonyms: FGF-6-, FGF6-
• Gene: Fgf6 Location: Chr6:126992505-127001681 bp, + strand Genetic Position: Chr6, 61.92 cM, cytoband F3-G1
• Alliance: Fgf6^tm1Thbr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:42574
• Parent Cell Line: J1 (ES Cell)
• Strain of Origin: 129S4/SvJae

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A neomycin resistance cassette replaced 3.8 kb of sequence. Most of exon 1, intron 1, exon 2 and part of exon 2 were deleted. (J:42574)
• Inheritance: Recessive

Expression

In Mice Carrying this Mutation:	7 assay results
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fgf6 Mutation: 10 strains or lines available

References

• Original: J:42574 Floss T, et al., A role for FGF-6 in skeletal muscle regeneration. Genes Dev. 1997 Aug 15;11(16):2040-51
• All: 2 reference(s)