Cdkn2d^tm1Maro
Targeted Allele Detail

Summary

• Symbol: Cdkn2d^tm1Maro
• Name: cyclin dependent kinase inhibitor 2D; targeted mutation 1, Martine F Roussel
• MGI ID: MGI:1927668
• Synonyms: INK4d-
• Gene: Cdkn2d Location: Chr9:21199759-21202553 bp, - strand Genetic Position: Chr9, 7.76 cM
• Alliance: Cdkn2d^tm1Maro page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:58959
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• Insertion of a LacZ-neomycin fusion gene (beta-geo) into the second exon of the INK4d gene. (J:58959)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Tumor Data

List all tumor models in MMHCdb carrying Cdkn2d^tm1Maro

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Cdkn2d Mutation: 25 strains or lines available

References

• Original: J:58959 Zindy F, et al., INK4d-deficient mice are fertile despite testicular atrophy. Mol Cell Biol. 2000 Jan;20(1):372-8
• All: 16 reference(s)