Hoxd9^tm1Emca
Targeted Allele Detail

Summary

• Symbol: Hoxd9^tm1Emca
• Name: homeobox D9; targeted mutation 1, Ellen M Carpenter
• MGI ID: MGI:1927870
• Gene: Hoxd9 Location: Chr2:74528107-74530552 bp, + strand Genetic Position: Chr2, 44.13 cM
• Alliance: Hoxd9^tm1Emca page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:59070
• Parent Cell Line: CC1.2 (ES Cell)
• Strain of Origin: 129S7/SvEvBrd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• Mutation details: A neo cassette was inserted into exon 2. This insertion is predicted to eliminate the activity of the homeodomain. (J:59070)
• Inheritance: Not Specified

Expression

In Mice Carrying this Mutation:

2 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hoxd9 Mutation: 16 strains or lines available

References

• Original: J:59070 de la Cruz CC, et al., Targeted disruption of Hoxd9 and Hoxd10 alters locomotor behavior, vertebral identity, and peripheral nervous system development. Dev Biol. 1999 Dec 15;216(2):595-610
• All: 1 reference(s)