Hoxb1^tm5Mrc
Targeted Allele Detail

Summary

• Symbol: Hoxb1^tm5Mrc
• Name: homeobox B1; targeted mutation 5, Mario R Capecchi
• MGI ID: MGI:1928090
• Synonyms: Hoxb1^GFP
• Gene: Hoxb1 Location: Chr11:96256578-96259082 bp, + strand Genetic Position: Chr11, 59.86 cM
• Alliance: Hoxb1^tm5Mrc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:65599
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: GFP was inserted in-frame into the first coding exon of the Hoxb1 gene. An adjacent loxP flanked neomycin cassette was removed via a cre-mediated recombination event. (J:65599)

Expression

In Mice Carrying this Mutation:	161 assay results 3 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hoxb1 Mutation: 24 strains or lines available

References

• Original: J:65599 Gaufo GO, et al., Hoxb1 controls effectors of sonic hedgehog and mash1 signaling pathways. Development. 2000 Dec;127(24):5343-54
• All: 9 reference(s)