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Trim28tm1Ipc
Targeted Allele Detail
Summary
Symbol: Trim28tm1Ipc
Name: tripartite motif-containing 28; targeted mutation 1, Pierre Chambon
MGI ID: MGI:1928908
Synonyms: Kap1F, L3
Gene: Trim28  Location: Chr7:12758079-12764959 bp, + strand  Genetic Position: Chr7, 7.73 cM, cytoband A2
Alliance: Trim28tm1Ipc page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:62628
Parent Cell Line:  H1 (ES Cell)
Strain of Origin:  129S2/SvPas
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsInsertion of a PGK-neomycin cassette and loxP sites as follows: A PGK-neomycin cassette flanked by two loxP sites was introduced into intron 3 and a loxP site was introduced into intron 14. (J:62628, J:171108)
Inheritance:    Recessive
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Tumor Data
List all tumor models in MMHCdb carrying Trim28tm1Ipc
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Trim28 Mutation:  36 strains or lines available
References
Original:  J:62628 Cammas F, et al., Mice lacking the transcriptional corepressor TIF1beta are defective in early postimplantation development. Development. 2000 Jul;127(13):2955-63
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory