Foxf1^tm1Pca
Targeted Allele Detail

Summary

• Symbol: Foxf1^tm1Pca
• Name: forkhead box F1; targeted mutation 1, Peter Carlsson
• MGI ID: MGI:1929432
• Synonyms: Foxf1-
• Gene: Foxf1 Location: Chr8:121811125-121814883 bp, + strand Genetic Position: Chr8, 70.31 cM, cytoband E1
• Alliance: Foxf1^tm1Pca page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:66591
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Replacement of sequences encoding the forkhead box with a neomycin cassette. (J:66591)
• Inheritance: Recessive

Expression

In Mice Carrying this Mutation:	49 assay results
In Structures Affected by this Mutation:	6 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Foxf1 Mutation: 13 strains or lines available

Notes

The targeting construct was electroporated into two ES cell lines, RW4, derived from 129X1/SvJ, and E14, derived from 129P2/OlaHsd.

References

• Original: J:66591 Mahlapuu M, et al., The forkhead transcription factor Foxf1 is required for differentiation of extra-embryonic and lateral plate mesoderm. Development. 2001 Jan;128(2):155-66
• All: 6 reference(s)