Tgm3^we-Bkr
Spontaneous Allele Detail

Summary

• Symbol: Tgm3^we-Bkr
• Name: transglutaminase 3, E polypeptide; wellhaarig Bunker
• MGI ID: MGI:1929708
• Gene: Tgm3 Location: Chr2:129854269-129892319 bp, + strand Genetic Position: Chr2, 63.19 cM
• Alliance: Tgm3^we-Bkr page

Mutation origin

• Strain of Origin: B10.129P-Il4i1^H46-b Emp3^b Oca2^p Selenos^H47-b/(21M)Sn

Mutation description

• Allele Type: Spontaneous (Not Specified)
• Mutation: Single point mutation
• Mutation details: A spontaneous C-to-T point mutation (c.896C>T) in exon 7s substitute a highly-conserved polar serine with a non-polar leucine residue at position 299 (p.S299L). (J:225940)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Tgm3 Mutation: 55 strains or lines available

References

• Original: J:8296 Graff RJ, et al., Abnormal bone production associated with mutant mouse genes pa and we. J Hered. 1986 Mar-Apr;77(2):109-13
• All: 3 reference(s)