Ntf5^tm1Gdy
Targeted Allele Detail

Summary

• Symbol: Ntf5^tm1Gdy
• Name: neurotrophin 5; targeted mutation 1, George D Yancopoulos
• MGI ID: MGI:1930044
• Synonyms: NT4-
• Gene: Ntf5 Location: Chr7:45063119-45066603 bp, + strand Genetic Position: Chr7, 29.3 cM
• Alliance: Ntf5^tm1Gdy page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:25565
• Parent Cell Line: E14.1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Replacement of 600bp of the only coding exon of the Ntf5 gene with a neomycin cassette. (J:25565)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ntf5 Mutation: 12 strains or lines available

References

• Original: J:25565 Conover JC, et al., Neuronal deficits, not involving motor neurons, in mice lacking BDNF and/or NT4. Nature. 1995 May 18;375(6528):235-8
• All: 10 reference(s)