Gdf9^tm1Zuk
Targeted Allele Detail

Summary

• Symbol: Gdf9^tm1Zuk
• Name: growth differentiation factor 9; targeted mutation 1, Martin M Matzuk
• MGI ID: MGI:1930111
• Synonyms: Gdf9-, Gdf9^m1
• Gene: Gdf9 Location: Chr11:53321850-53328731 bp, + strand Genetic Position: Chr11, 31.94 cM
• Alliance: Gdf9^tm1Zuk page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:35782
• Parent Cell Line: AB2.1 (ES Cell)
• Strain of Origin: 129S7/SvEvBrd-Hprt1^b-m2

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: The deletion targeting vector generated a 1.1kb deletion including exon 2 which encodes the majority of the propeptide sequence and the complete mature sequence. (J:35782)

Expression

In Mice Carrying this Mutation:	11 assay results 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gdf9 Mutation: 35 strains or lines available

References

• Original: J:35782 Dong J, et al., Growth differentiation factor-9 is required during early ovarian folliculogenesis [see comments]. Nature. 1996 Oct 10;383(6600):531-5
• All: 19 reference(s)