Fgf4^tm1.1Mrt
Targeted Allele Detail

Summary

• Symbol: Fgf4^tm1.1Mrt
• Name: fibroblast growth factor 4; targeted mutation 1.1, Gail R Martin
• MGI ID: MGI:1931061
• Synonyms: Fgf4^neo
• Gene: Fgf4 Location: Chr7:144415123-144418982 bp, + strand Genetic Position: Chr7, 88.88 cM
• Alliance: Fgf4^tm1.1Mrt page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:61886
• Parent Cell Line: CGR8 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A single loxP site followed by an frt-flanked neomycin selection cassette was inserted into intron 1 and a single loxP site was inserted into the 3' flanking sequences of the gene. (J:61886)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fgf4 Mutation: 30 strains or lines available

References

• Original: J:61886 Sun X, et al., Conditional inactivation of Fgf4 reveals complexity of signalling during limb bud development. Nat Genet. 2000 May;25(1):83-6
• All: 1 reference(s)