Fgf4^tm1Gol
Targeted Allele Detail

Summary

• Symbol: Fgf4^tm1Gol
• Name: fibroblast growth factor 4; targeted mutation 1, Mitchell Goldfarb
• MGI ID: MGI:1931072
• Synonyms: Fgf4-
• Gene: Fgf4 Location: Chr7:144415123-144418982 bp, + strand Genetic Position: Chr7, 88.88 cM
• Alliance: Fgf4^tm1Gol page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:22275
• Parent Cell Line: CB1-4 (ES Cell)
• Strain of Origin: C57BL/6J x (Rb(11.16)2H x Rb(16.17)32Lub)F1

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A promoterless neomycin gene was inserted into exon 1, and sequences corresponding to the first 109 amino acids were deleted. (J:22275)

Expression

In Mice Carrying this Mutation:	60 assay results 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fgf4 Mutation: 30 strains or lines available

References

• Original: J:22275 Feldman B, et al., Requirement of FGF-4 for postimplantation mouse development. Science. 1995 Jan 13;267(5195):246-9
• All: 7 reference(s)