Galnt1^tm1Jxm
Targeted Allele Detail

Summary

• Symbol: Galnt1^tm1Jxm
• Name: polypeptide N-acetylgalactosaminyltransferase 1; targeted mutation 1, Jamey Marth
• MGI ID: MGI:1931149
• Gene: Galnt1 Location: Chr18:24338401-24419873 bp, + strand Genetic Position: Chr18, 12.9 cM, cytoband B1
• Alliance: Galnt1^tm1Jxm page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:119128
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was placed downstream of an exon and a floxed neomycin-thymidine kinase expression cassette was inserted into the upstream intron. Transient expression from an injected Cre plasmid removed the neomycin-thymidine cassette, but left the floxed exon, prior to production of chimeric mice. (J:119128)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Galnt1 Mutation: 138 strains or lines available

References

• Original: J:119128 Marth J, Targeted mutation of the Galnt1 gene. MGI Direct Data Submission. 2007
• All: 2 reference(s)