Nkx3-2^tm1Bobh
Targeted Allele Detail

Summary

• Symbol: Nkx3-2^tm1Bobh
• Name: NK3 homeobox 2; targeted mutation 1, Robert E Hill
• MGI ID: MGI:1931319
• Synonyms: Bapx1 -, Nkx3.2 -
• Gene: Nkx3-2 Location: Chr5:41918826-41921563 bp, - strand Genetic Position: Chr5, 22.58 cM
• Alliance: Nkx3-2^tm1Bobh page

Skeletal phenotypes of E18.5 Nkx3-2^tm1Bobh/Nkx3-2^tm1Bobh fetuses

Show the 3 phenotype image(s) involving this allele.

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:57112
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• Insertion of a neomycin cassette into the coding region of exon 1. (J:57112)
• Inheritance: Recessive

Expression

In Mice Carrying this Mutation:	22 assay results
In Structures Affected by this Mutation:	21 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nkx3-2 Mutation: 21 strains or lines available

References

• Original: J:57112 Lettice LA, et al., The mouse bagpipe gene controls development of axial skeleton, skull, and spleen. Proc Natl Acad Sci U S A. 1999 Aug 17;96(17):9695-700
• All: 7 reference(s)