F5^tm1Dgi
Targeted Allele Detail

Summary

• Symbol: F5^tm1Dgi
• Name: coagulation factor V; targeted mutation 1, David Ginsburg
• MGI ID: MGI:1931525
• Synonyms: Fv^-
• Gene: F5 Location: Chr1:163979407-164047846 bp, + strand Genetic Position: Chr1, 71.46 cM
• Alliance: F5^tm1Dgi page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:36444
• Parent Cell Line: D3 (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Replacement of exons 8-11 with a neomycin cassette. (J:36444)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any F5 Mutation: 159 strains or lines available

References

• Original: J:36444 Cui J, et al., Fatal haemorrhage and incomplete block to embryogenesis in mice lacking coagulation factor V. Nature. 1996 Nov 7;384(6604):66-8
• All: 9 reference(s)