Cd36^tm1Mfe
Targeted Allele Detail

Summary

• Symbol: Cd36^tm1Mfe
• Name: CD36 molecule; targeted mutation 1, Maria Febbraio
• MGI ID: MGI:1931790
• Synonyms: Cd36-, CD36 KO, CD36KO, FAT/CD36^-
• Gene: Cd36 Location: Chr5:17986688-18093799 bp, - strand Genetic Position: Chr5, 8.11 cM
• Alliance: Cd36^tm1Mfe page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:56081
• Parent Cell Line: CJ7 (ES Cell)
• Strain of Origin: 129S1/Sv-Oca2⁺ Tyr⁺ Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• A neomycin cassette replaced a 1kb fragment including the transcription start site. (J:56081)
• Inheritance: Recessive

Disease models

Expression

In Mice Carrying this Mutation:	2 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	15 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Cd36 Mutation: 34 strains or lines available

References

• Original: J:56081 Febbraio M, et al., A null mutation in murine CD36 reveals an important role in fatty acid and lipoprotein metabolism. J Biol Chem. 1999 Jul 2;274(27):19055-62
• All: 219 reference(s)