Il13^tm1Anjm
Targeted Allele Detail

Summary

• Symbol: Il13^tm1Anjm
• Name: interleukin 13; targeted mutation 1, Andrew NJ McKenzie
• MGI ID: MGI:1931821
• Synonyms: il13^-, IL-13-
• Gene: Il13 Location: Chr11:53522151-53525529 bp, - strand Genetic Position: Chr11, 31.98 cM
• Alliance: Il13^tm1Anjm page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:67970
• Parent Cell Line: E14.1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• An IRES-lacZ and loxP flanked neomycin resistance gene cassette were inserted into exon 1. (J:67970)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Il13 Mutation: 30 strains or lines available

References

• Original: J:67970 McKenzie GJ, et al., A distinct role for interleukin-13 in Th2-cell-mediated immune responses. Curr Biol. 1998 Mar 12;8(6):339-42
• All: 60 reference(s)