Ccr1^tm1Cge
Targeted Allele Detail

Summary

• Symbol: Ccr1^tm1Cge
• Name: C-C motif chemokine receptor 1; targeted mutation 1, Craig Gerard
• MGI ID: MGI:1931849
• Synonyms: CCR1-
• Gene: Ccr1 Location: Chr9:123762163-123768729 bp, - strand Genetic Position: Chr9, 75.05 cM, cytoband F
• Alliance: Ccr1^tm1Cge page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:43569
• Parent Cell Line: J1 (ES Cell)
• Strain of Origin: 129S4/SvJae

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A PGK-neomycin resistance cassette replaced most of the carboxy terminal coding sequence. Transcript was not detected in bone marrow cells of homozygous mutant animals. (J:43569)

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ccr1 Mutation: 40 strains or lines available

References

• Original: J:43569 Gerard C, et al., Targeted disruption of the beta-chemokine receptor CCR1 protects against pancreatitis-associated lung injury. J Clin Invest. 1997 Oct 15;100(8):2022-7
• All: 20 reference(s)