Clns1a^tm1Kwn
Targeted Allele Detail

Summary

• Symbol: Clns1a^tm1Kwn
• Name: chloride channel, nucleotide-sensitive, 1A; targeted mutation 1, Kevin D Wickman
• MGI ID: MGI:1934011
• Synonyms: ICln^KO
• Gene: Clns1a Location: Chr7:97345864-97370000 bp, + strand Genetic Position: Chr7, 53.57 cM, cytoband E3
• Alliance: Clns1a^tm1Kwn page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:61831
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129/Sv

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• The first coding exon was replaced by a neomycin cassette. (J:61831)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Clns1a Mutation: 17 strains or lines available

References

• Original: J:61831 Pu WT, et al., ICln is essential for cellular and early embryonic viability. J Biol Chem. 2000 Apr 28;275(17):12363-6
• All: 1 reference(s)