Tacr1^tm1Nge
Targeted Allele Detail

Summary

• Symbol: Tacr1^tm1Nge
• Name: tachykinin receptor 1; targeted mutation 1, Norma P Gerard
• MGI ID: MGI:1934027
• Synonyms: NK1-, NK-1R-, NK1R^-
• Gene: Tacr1 Location: Chr6:82379315-82537085 bp, + strand Genetic Position: Chr6, 35.94 cM, cytoband D1
• Alliance: Tacr1^tm1Nge page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:35529
• Parent Cell Line: J1 (ES Cell)
• Strain of Origin: 129S4/SvJae

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A LacZ-PGK-neomycin resistance cassette replaced part of exon 1, including the initiating methionine codon. (J:35529)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tacr1 Mutation: 40 strains or lines available

References

• Original: J:35529 Bozic CR, et al., Neurogenic amplification of immune complex inflammation. Science. 1996 Sep 20;273(5282):1722-5
• All: 42 reference(s)