Vangl2^Lp-m1Jus
Chemically induced Allele Detail

Summary

• Symbol: Vangl2^Lp-m1Jus
• Name: VANGL planar cell polarity 2; loop tail, mutation 1, Monica J Justice
• MGI ID: MGI:1934175
• Synonyms: Lp^m1J
• Gene: Vangl2 Location: Chr1:171828527-171856011 bp, - strand Genetic Position: Chr1, 79.54 cM
• Alliance: Vangl2^Lp-m1Jus page

Mutation origin

• Strain of Origin: (101/Rl x C3H/Rl)F1

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: A transversion point mutation that alters a T to an A at position 765. This mutation is predicted to change aspartate 255 to glutamate in the encoded protein. (J:70272)
• Inheritance: Semidominant

Expression

In Mice Carrying this Mutation:	22 assay results
In Structures Affected by this Mutation:	4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Vangl2 Mutation: 34 strains or lines available

References

• Original: J:68823 Kibar Z, et al., Identification of a new chemically induced allele (lp(m1jus)) at the loop-tail locus: morphology, histology, and genetic mapping. Genomics. 2001 Mar 15;72(3):331-7
• All: 9 reference(s)