Cxcr4^tm1Yzo
Targeted Allele Detail

Summary

• Symbol: Cxcr4^tm1Yzo
• Name: C-X-C motif chemokine receptor 4; targeted mutation 1, Yong-Rui Zou
• MGI ID: MGI:1934407
• Synonyms: CXCR4-
• Gene: Cxcr4 Location: Chr1:128515936-128520030 bp, - strand Genetic Position: Chr1, 56.43 cM
• Alliance: Cxcr4^tm1Yzo page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:69255
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• A loxP-flanked neomycin resistance cassette was inserted into the second exon. (J:69255)

Expression

In Mice Carrying this Mutation:	36 assay results
In Structures Affected by this Mutation:	6 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cxcr4 Mutation: 46 strains or lines available

References

• Original: J:69255 Zou YR, et al., Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development. Nature. 1998 Jun 11;393(6685):595-9
• All: 33 reference(s)