Amn^amn
Transgenic Allele Detail

Summary

• Symbol: Amn^amn
• Name: amnionless
• MGI ID: MGI:2135304
• Synonyms: amn, Tg(CD8A)T81-3Ehl
• Gene: Amn Location: Chr12:111237530-111242860 bp, + strand Genetic Position: Chr12, 60.94 cM
• Alliance: Amn^amn page

Transgene origin

• Strain of Origin: C57BL/6J

Transgene description

• Transgene Type: Transgenic
• Mutation: Insertion
• Mutation details: Integration of three to five copies of the human CD8A transgene into the Amn gene caused a small deletion at the insertion site. Heterozygote mutant mice express low levels of human CD8A mRNA in spleen, thymus, and brain. (J:68615)

Expression

In Structures Affected by this Mutation:

5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Amn Mutation: 19 strains or lines available

Notes

At one time amn was thought to be an allele of Traf3 J:34163.

References

• Original: J:34163 Wang X, et al., A candidate gene for the amnionless gastrulation stage mouse mutation encodes a TRAF-related protein. Dev Biol. 1996 Jul 10;177(1):274-90
• All: 5 reference(s)