Amn^tm1Ehl
Targeted Allele Detail

Summary

• Symbol: Amn^tm1Ehl
• Name: amnionless; targeted mutation 1, Elizabeth Lacy
• MGI ID: MGI:2135454
• Synonyms: Amn^gfp
• Gene: Amn Location: Chr12:111237530-111242860 bp, + strand Genetic Position: Chr12, 60.94 cM
• Alliance: Amn^tm1Ehl page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:68615
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129X1/SvJ

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Insertion of an eGFP lox-MC1-neo-lox cassette replaced the ORF. (J:68615)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Amn Mutation: 19 strains or lines available

References

• Original: J:68615 Kalantry S, et al., The amnionless gene, essential for mouse gastrulation, encodes a visceral-endoderm-specific protein with an extracellular cysteine-rich domain. Nat Genet. 2001 Apr;27(4):412-6
• All: 2 reference(s)