Eed^l7Rn5-1989SB
Chemically induced Allele Detail

Summary

• Symbol: Eed^l7Rn5-1989SB
• Name: embryonic ectoderm development; lethal, Chr 7, Rinchik 5, 1989SB
• MGI ID: MGI:2135817
• Synonyms: 17Rn5^1989SB, 1989SB, eed¹⁹⁸⁹, Eed^hypo, eed^hypomorph, Eedl7^Rn5-1R
• Gene: Eed Location: Chr7:89603862-89630184 bp, - strand Genetic Position: Chr7, 50.42 cM
• Alliance: Eed^l7Rn5-1989SB page

Mutation origin

• Strain of Origin: BALB/cRl

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: Positional cloning of the embryonic ectoderm development locus identified a transverstion of thymine at position 1031 to adenosine in the 1989SB ENU induced allele. The amino acid change of a polar Asn residue to a hydrophobic Ile at amino acid position 193 lies the second WD motif. (J:35419)
• Inheritance: Recessive

Expression

In Mice Carrying this Mutation:

269 assay results 1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Eed Mutation: 116 strains or lines available

References

• Original: J:12917 Rinchik EM, et al., N-ethyl-N-nitrosourea-induced prenatally lethal mutations define at least two complementation groups within the embryonic ectoderm development (eed) locus in mouse chromosome 7. Mamm Genome. 1993;4(7):349-53
• All: 11 reference(s)