Fgf9^tm1Dor
Targeted Allele Detail

Summary

• Symbol: Fgf9^tm1Dor
• Name: fibroblast growth factor 9; targeted mutation 1, David Ornitz
• MGI ID: MGI:2135961
• Synonyms: Fgf9^-
• Gene: Fgf9 Location: Chr14:58308543-58350311 bp, + strand Genetic Position: Chr14, 30.51 cM, cytoband D
• Alliance: Fgf9^tm1Dor page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:68379
• Parent Cell Line: SM1 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Replacement of 500 bp of genomic sequence with a neomycin resistance cassette, resulting in a deletion eliminating 224 bp of the 277 bp in the protein-coding region of exon 1 and extending into the first intron. (J:68379)
• Inheritance: Recessive

Expression

In Mice Carrying this Mutation:	48 assay results
In Structures Affected by this Mutation:	15 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fgf9 Mutation: 17 strains or lines available

References

• Original: J:68379 Colvin JS, et al., Male-to-female sex reversal in mice lacking fibroblast growth factor 9. Cell. 2001 Mar 23;104(6):875-89
• All: 39 reference(s)