Hoxa11^tm1Ssp
Targeted Allele Detail

Summary

• Symbol: Hoxa11^tm1Ssp
• Name: homeobox A11; targeted mutation 1, S Steven Potter
• MGI ID: MGI:2135973
• Synonyms: Hoxa11^-, Hox A11^-, Hoxa-11^CIN
• Gene: Hoxa11 Location: Chr6:52219086-52222784 bp, - strand Genetic Position: Chr6, 25.4 cM
• Alliance: Hoxa11^tm1Ssp page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:16079
• Parent Cell Line: D3 (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Deletion of a 2.7 kb region including the 3' portion of the gene encoding the homeobox domain. (J:16079)

Expression

In Mice Carrying this Mutation:	31 assay results 2 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	17 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hoxa11 Mutation: 11 strains or lines available

References

• Original: J:16079 Small KM, et al., Homeotic transformations and limb defects in Hox A11 mutant mice. Genes Dev. 1993 Dec;7(12A):2318-28
• All: 19 reference(s)