Emx2^tm1Sia
Targeted Allele Detail

Summary

• Symbol: Emx2^tm1Sia
• Name: empty spiracles homeobox 2; targeted mutation 1, Shinichi Aizawa
• MGI ID: MGI:2136350
• Synonyms: Emx2^HD/HD
• Gene: Emx2 Location: Chr19:59447122-59453789 bp, + strand Genetic Position: Chr19, 56.28 cM
• Alliance: Emx2^tm1Sia page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:38397
• Parent Cell Line: TT2 (ES Cell)
• Strain of Origin: (C57BL/6NCrlj x CBA/JNCrlj)F1

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• Mutation details: A neomycin cassette was inserted into the second exon, in front of the sequences encoding the homeobox domain. (J:38397)

Expression

In Mice Carrying this Mutation:	251 assay results 2 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	16 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Emx2 Mutation: 24 strains or lines available

References

• Original: J:38397 Yoshida M, et al., Emx1 and Emx2 functions in development of dorsal telencephalon. Development. 1997 Jan;124(1):101-11
• All: 17 reference(s)