Lbx1^tm1Cbm
Targeted Allele Detail

Summary

• Symbol: Lbx1^tm1Cbm
• Name: ladybird homeobox 1; targeted mutation 1, Carmen Birchmeier
• MGI ID: MGI:2136963
• Synonyms: Lbx1^LacZ
• Gene: Lbx1 Location: Chr19:45221123-45224251 bp, - strand Genetic Position: Chr19, 38.61 cM, cytoband D
• Alliance: Lbx1^tm1Cbm page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:56466
• Parent Cell Line: E14.1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: LacZ was fused to the first 60 amino acids of exon 1, a neo cassette was inserted 3' of LacZ and all C terminal Lbx1h coding sequences including the homeodomain were deleted. (J:56466)

Expression

In Mice Carrying this Mutation:

41 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Lbx1 Mutation: 13 strains or lines available

References

• Original: J:56466 Brohmann H, et al., The role of Lbx1 in migration of muscle precursor cells. Development. 2000 Jan;127(2):437-45
• All: 4 reference(s)