Mesp2^tm1Ysa
Targeted Allele Detail

Summary

• Symbol: Mesp2^tm1Ysa
• Name: mesoderm posterior 2; targeted mutation 1, Yumiko Saga
• MGI ID: MGI:2137558
• Synonyms: P2v
• Gene: Mesp2 Location: Chr7:79460475-79463179 bp, + strand Genetic Position: Chr7, 45.18 cM
• Alliance: Mesp2^tm1Ysa page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:42014
• Parent Cell Line: TT2 (ES Cell)
• Strain of Origin: (C57BL/6NCrlj x CBA/JNCrlj)F1

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• A PGK-neomycin resistance cassette replaced exons 1 and 2. (J:42014)

Expression

In Mice Carrying this Mutation:	32 assay results
In Structures Affected by this Mutation:	13 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mesp2 Mutation: 30 strains or lines available

References

• Original: J:42014 Saga Y, et al., Mesp2: a novel mouse gene expressed in the presegmented mesoderm and essential for segmentation initiation. Genes Dev. 1997 Jul 15;11(14):1827-39
• All: 6 reference(s)