Map7^{Gt(ROSABetageo)1Sor}
Gene trapped Allele Detail

Summary

• Symbol: Map7^{Gt(ROSABetageo)1Sor}
• Name: microtubule-associated protein 7; gene trap 1, Philippe Soriano
• MGI ID: MGI:2148221
• Synonyms: E-MAP-115^-, Mtap7^Gt1Sor
• Gene: Map7 Location: Chr10:20024666-20157336 bp, + strand Genetic Position: Chr10, 9.75 cM
• Alliance: Map7^{Gt(ROSABetageo)1Sor} page

Mutation origin

• Mutant Cell Line: ROSA63
• Germline Transmission: Earliest citation of germline transmission: J:62570
• Parent Cell Line: AK7 (ES Cell)
• Strain of Origin: 129S4/SvJaeSor

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: ROSABetageo*
• Mutation details: A lacZ-neomycin gene trap vector inserted in frame at a site that encodes alanine 23. Northern analysis did not detect wild-type mRNA transcripts in homozygous mutant mice. (J:62570)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  FHCRC-GT-ROSA63	CG465914 ; (MGI Seq Detail)	5' RACE	Chr10:20024748-20024825 bp (+)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  168 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Expression

In Mice Carrying this Mutation:	2 assay results
In Structures Affected by this Mutation:	5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Map7 Mutation: 240 strains or lines available

References

• Original: J:62570 Komada M, et al., E-MAP-115, encoding a microtubule-associated protein, is a retinoic acid-inducible gene required for spermatogenesis. Genes Dev. 2000 Jun 1;14(11):1332-42
• All: 3 reference(s)