Maf^tm1Gsb
Targeted Allele Detail

Summary

• Symbol: Maf^tm1Gsb
• Name: MAF bZIP transcription factor; targeted mutation 1, Gregory S Barsh
• MGI ID: MGI:2148635
• Synonyms: Maf^lacZ
• Gene: Maf Location: Chr8:116429992-116433633 bp, - strand Genetic Position: Chr8, 62.61 cM
• Alliance: Maf^tm1Gsb page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:56583
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Replacement of sequences encoding the C-terminal 351 amino acids with a lacZ gene. This allele expresses a fusion protein of the first 19 amino acids of MAF fused to beta-galactosidase. (J:56583)

Expression

In Mice Carrying this Mutation:	137 assay results
In Structures Affected by this Mutation:	5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Maf Mutation: 27 strains or lines available

References

• Original: J:56583 Ring BZ, et al., Regulation of mouse lens fiber cell development and differentiation by the Maf gene. Development. 2000 Jan;127(2):307-17
• All: 2 reference(s)