Gsx2^tm1Ssp
Targeted Allele Detail

Summary

• Symbol: Gsx2^tm1Ssp
• Name: GS homeobox 2; targeted mutation 1, S Steven Potter
• MGI ID: MGI:2150162
• Synonyms: Gsh-2^-
• Gene: Gsx2 Location: Chr5:75236262-75238554 bp, + strand Genetic Position: Chr5, 39.55 cM
• Alliance: Gsx2^tm1Ssp page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:44324
• Parent Cell Line: D3 (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A neomycin resistance cassette replaced a 487 bp region encoding the last 40 amino acids of the homeodomain and the carboxy terminus. (J:44324)

Expression

In Mice Carrying this Mutation:	214 assay results
In Structures Affected by this Mutation:	6 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gsx2 Mutation: 18 strains or lines available

References

• Original: J:44324 Szucsik JC, et al., Altered forebrain and hindbrain development in mice mutant for the Gsh-2 homeobox gene. Dev Biol. 1997 Nov 15;191(2):230-42
• All: 19 reference(s)