Hoxa7^tm1Mrc
Targeted Allele Detail

Summary

• Symbol: Hoxa7^tm1Mrc
• Name: homeobox A7; targeted mutation 1, Mario R Capecchi
• MGI ID: MGI:2150400
• Synonyms: Hoxa7 -
• Gene: Hoxa7 Location: Chr6:52191471-52198757 bp, - strand Genetic Position: Chr6, 25.4 cM
• Alliance: Hoxa7^tm1Mrc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:50942
• Parent Cell Line: CC1.2 (ES Cell)
• Strain of Origin: 129S7/SvEvBrd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• A neomycin resistance cassette was inserted into the sequences encoding the homeobox domain. (J:50942)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hoxa7 Mutation: 17 strains or lines available

References

• Original: J:50942 Chen F, et al., Analysis of Hoxa7/Hoxb7 mutants suggests periodicity in the generation of the different sets of vertebrae. Mech Dev. 1998 Sep;77(1):49-57
• All: 4 reference(s)