Hoxd9^tm1Ipc
Targeted Allele Detail

Summary

• Symbol: Hoxd9^tm1Ipc
• Name: homeobox D9; targeted mutation 1, I Pierre Chambon
• MGI ID: MGI:2150414
• Synonyms: Hoxd-9-
• Gene: Hoxd9 Location: Chr2:74528107-74530552 bp, + strand Genetic Position: Chr2, 44.13 cM
• Alliance: Hoxd9^tm1Ipc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:31476
• Parent Cell Line: D3 (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• A neomycin cassette was inserted into the sequences encoding the homeobox domain. (J:31476)

Expression

In Structures Affected by this Mutation:

5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hoxd9 Mutation: 16 strains or lines available

References

• Original: J:31476 Fromental-Ramain C, et al., Specific and redundant functions of the paralogous Hoxa-9 and Hoxd-9 genes in forelimb and axial skeleton patterning. Development. 1996 Feb;122(2):461-72
• All: 1 reference(s)