Hoxa10^tm1Rilm
Targeted Allele Detail

Summary

• Symbol: Hoxa10^tm1Rilm
• Name: homeobox A10; targeted mutation 1, Richard Maas
• MGI ID: MGI:2150430
• Synonyms: Hoxa-10-
• Gene: Hoxa10 Location: Chr6:52208177-52217658 bp, - strand Genetic Position: Chr6, 25.4 cM
• Alliance: Hoxa10^tm1Rilm page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:24123
• Parent Cell Line: J1 (ES Cell)
• Strain of Origin: 129S4/SvJae

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• Mutation details: A neomycin resistance cassette was inserted into the sequences encoding the homeobox domain. No transcript was detected by RT-PCR analysis on mRNA derived from adult kidney of homozygous mice. (J:24123)

Expression

In Mice Carrying this Mutation:	4 assay results
In Structures Affected by this Mutation:	8 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hoxa10 Mutation: 19 strains or lines available

References

• Original: J:24123 Satokata I, et al., Sexually dimorphic sterility phenotypes in Hoxa10-deficient mice. Nature. 1995 Mar 30;374(6521):460-3
• All: 14 reference(s)