Hoxa10^tm1Ipc
Targeted Allele Detail

Summary

• Symbol: Hoxa10^tm1Ipc
• Name: homeobox A10; targeted mutation 1, I Pierre Chambon
• MGI ID: MGI:2150505
• Synonyms: Hoxa-10^-
• Gene: Hoxa10 Location: Chr6:52208177-52217658 bp, - strand Genetic Position: Chr6, 25.4 cM
• Alliance: Hoxa10^tm1Ipc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:28593
• Parent Cell Line: D3 (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• A neomycin resistance cassette was inserted into sequences encoding the homeobox domain. (J:28593)

Expression

In Mice Carrying this Mutation:	12 assay results
In Structures Affected by this Mutation:	16 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hoxa10 Mutation: 19 strains or lines available

References

• Original: J:28593 Rijli FM, et al., Cryptorchidism and homeotic transformations of spinal nerves and vertebrae in Hoxa-10 mutant mice. Proc Natl Acad Sci U S A. 1995 Aug 29;92(18):8185-9
• All: 2 reference(s)